Research Interest:Molecular Biology of Human Immunodeficiency Virus (HIV) virus, Immunology, Virology and Infectious diseases

Research Interest: Drug Resistance Is A Major Obstacle For Most Anticancer Therapeutics. Several Clinical Studies Have Described Reduced Response To Antiangiogenic Therapy Targeting VEGF Pathway Over Time Followed By Regrowth Of Treated Tumors. As Tumor Angiogenesis Is Governed By Multiple Pathways

Research Interest:Understand the mechanisms of HIV-1 primary infection, and to elucidate the host restriction and viral latency.

Research Interest: Primarily Focuses On HIV/AIDS And Mental Health Among People Of African Descent And Immigrants/Migrants. Other Research Interests Include But Not Limited To: Alcohol And Drug Use, Community Based Participatory Research, Other Sexually Transmitted Infections, Health Literacy And Physical Activity, Instrument Design And Testing, Program Planning, Implementation, Community Coalition-Building; And Monitoring And Evaluation.

Research Interest: Revolve Around Adolescent Sexual Health, With Respect To Sexually Transmitted Infections And HIV. I Have Research Expertise In Clinical Research, Randomized Trial Design, As Well As Use Of Large Databases.

Research Interest: Trauma, PTSD, Temperament, Social Support, Stress Coping, HIV/AIDS, Chronic Pain

Research Interest:COPD and Asthma, Occupational Respiratory Diseases, Lung cancer, Tobacco Smoking and Cessation, Sleep Apnea

Research Interest: Novel Immunotherapies Based On Dendritic Cells And Therapeutical Antibodies

Research Interest: Health Sciences, Nursing, Contagious Diseases of Nursing.

Research Interest: Geography of HIV/AIDS; Sub-Saharan Africa; South-East Asia; Sustainable Development; Development Studies; Global Health Issues; Poverty; Globalization; Regional Development.

Research Interest: Reflects a Nice Blend of Trajectory of Advance Research in Organic, Bio-Organic And Medicinal Chemistry Seeking Problem To Human Diseases, Like AIDS, Cervical Cancer, Japanese Encephalitis Fever, And Other Microbial Diseases.

Born in Cosenza (ITALY), November 23, 1967
ACTUAL POSITION
Researcher in Microbiology and Clinical Microbiology (06/A3, MED/07), Department of Pharmacy and Health and Nutrition Sciences, University of Calabria, Italy.
EDUCATION
1993-Degree cum laude in Biological Sciences at the University of Siena, Italy.
1994-Qualification to practice as a biologist at the University of Siena, Italy.
PROFESSIONAL CARREER
1994-Professional collaboration in the Multi-annual Plurifund Programs of the European Union (P.O.P. 90-93) on the "Endocrine typology of patients with hormone-dependent tumors", Health Center, University of Calabria.
1995-1997-Professional collaboration in a multi-center research program conducted in 5 European Union countries on calcium intake and bone mass pick in young women (European CALEUR Study), Health Center, University of Calabria.
1997-1999-Professional collaborations with official positions in the research activities carried out by the Health Center, University of Calabria.
1997-to present-Professional collaboration in the Laboratory of Analysis of Clinical Chemistry and Toxicology, Health Center, University of Calabria.
2000-2004-Technical graduate health area, Health Center, University of Calabria.
2001-2002-Research fellow at the laboratory of Prof. Michael J. McPhaul of the Department of Internal Medicine, Division of Endocrinology and Metabolism-University of Texas Southwestern Medical Center-Dallas-Texas.

Research Interest: Virus proteins and cancer

List of Publications:
1.    HE W, MAZZUCA P, YUAN W, VARNEY K, BUGATTI A, CAGNOTTO A, GIAGULLI C, RUSNATI M, MARSICO S, DIOMEDE L, SALMONA M, CARUSO A, LU W, CACCURI F. (2018) Identification of amino acid residues critical for the B cell growth-promoting activity of HIV-1 matrix protein p17 variants. BIOCHIM. BIOPHYS. ACTA GEN. SUBJ. 2018 Sep 21; 1863(1): 13-24 doi: 10.1016/j.bbagen.2018.09.016. (I.F. 3,679)
2.    MARSICO S, CACCURI F, MAZZUCA P, APOSTOLI P, ROVERSI S, LORENZIN G, ZANI A, FIORENTINI S,  GIAGULLI C, CARUSO A (2018) Human lung epithelial cells support human metapneumovirus persistence by overtaking apoptosis. PATHOGENS AND DISEASE 76(2) doi: 10.1093/femspd/fty013 (IF 2,335)
3.    CACCURI F, GIORDANO F, BARONE I, MAZZUCA P, GIAGULLI C, ANDÒ S, CARUSO A, MARSICO S (2017). HIV-1 matrix protein p17 and its variants promote human triple negative breast cancer cell aggressiveness. INFECTIOUS AGENTS AND CANCER 12: 49. Doi: 10.1186/s13027-017-0160-7. (IF 1,422)
4.    GIAGULLI C, D'URSI P, HE W, ZORZAN S, CACCURI F, VARNEY K, ORRO A, MARSICO S, OTJACQUES B, LAUDANNA C, MILANESI L, DOLCETTI R, FIORENTINI S, LU W, CARUSO A (2017). A single amino acid substitution confers B-cell clonogenic activity to the HIV-1 matrix protein p17. SCI. REP. 7(1):6555. doi: 10.1038/s41598-017-06848-y. (IF 4,259)
5.    MAZZUCA P*, MARSICO S*, SCHULZE K, MITOLA S, PILS MC, GIAGULLI C, GUZMAN CA, CARUSO A, CACCURI F (2017). Role of autophagy in the HIV-1 matrix protein p17-driven lymphangiogenesis. J VIROL. 91(16). pii: e00801-17. doi: 10.1128/JVI.00801-17. (IF 4,663)
6.    BONOFIGLIO D, CATALANO S, PERRI A, SANTORO M, SICILIANO L, LOFARO D, GALLO M, MARSICO S, BRUNO R, GIORDANO C, BARONE I, ANDÒ S (2017). Monitoring the effects of iodine prophylaxis in the adult population of southern Italy with deficient and sufficient iodine intake levels: a cross-sectional, epidemiological study. BRITISH JOURNAL OF NUTRITION, 117(1):170-175, doi: 10.1017/S0007114516004499. (IF 3,706)
7.    CATALANO S, BARONE I, MARSICO S, BRUNO R, ANDÒ S (2016). Phosphorylation Processes Controlling Aromatase Activity in Breast Cancer: An Update. MINI REV MED CHEM.16(9):691-8. (IF 2,661)
8.    CACCURI F, MARSICO S, FIORENTINI S, CARUSO A, GIAGULLI C (2016). HIV-1 Matrix Protein p17 and its Receptors. CURR DRUG TARGETS, 17(1):23-32. (IF 3,236)
9.    DOLCETTI R, GIAGULLI C, HE W, SELLERI M, CACCURI F, EYZAGUIRRE L M, MAZZUCA P, CORBELLINI S, CAMPILONGO F, MARSICO S, GIOMBINI E, MURARO E, ROZERA G, DE PAOLI P, CARBONE A, CAPOBIANCHI M R, IPPOLITO G, FIORENTINI S, BLATTNER W A, LU W, GALLO R C, CARUSO A. (2015). Role of HIV-1 matrix protein p17 variants in lymphoma pathogenesis. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, vol. 112, p. 14331-14336, ISSN: 1091-6490, doi: 10.1073/pnas.1514748112. (IF 9,661)
10.    CACCURI F, RUECKERT C, GIAGULLI C, SCHULZE K, BASTA D, ZICARI S, MARSICO S, CERVI E, FIORENTINI S, SLEVIN M, GUZMAN CA, CARUSO A. (2014). HIV-1 matrix protein p17 promotes lymphangiogenesis and activates the endothelin-1/endothelin B receptor axis. ARTERIOSCLER THROMB VASC BIOL., 34(4):846-56. doi: 10.1161/ATVBAHA.113.302478. (IF 6,606)
11.    CACCURI F, GIAGULLI C, REICHELT J, MARTORELLI D, MARSICO S, BUGATTI A, BARONE I, RUSNATI M, GUZMAN CA, DOLCETTI R, CARUSO A (2014). Simian Immunodeficiency Virus and Human Immunodeficiency Virus Type 1 Matrix Proteins Specify Different Capabilities To Modulate B Cell Growth. JOURNAL OF VIROLOGY, vol. 88, ISSN: 0022-538X, doi:10.1128/JVI.03142-13 (IF 4,663)
12.    DE FRANCESCO EM, LAPPANO R, SANTOLLA MF, MARSICO S, CARUSO A, MAGGIOLINI M (2013). HIF-1alpha/GPER signaling mediates the expression of VEGF induced by hypoxia in breast cancer associated fibroblasts (CAFs) . BREAST CANCER RESEARCH, vol. 15, ISSN: 1465-5411, doi: 10.1186/bcr3458 (IF 6,345)
13.    GIAGULLI C, MAGIERA AK, BUGATTI A, CACCURI F, MARSICO S, RUSNATI M, VERMI W, FIORENTINI S, CARUSO A (2012). HIV-1 matrix protein p17 binds to the IL-8 receptor CXCR1 and shows IL-8-like chemokine activity on monocytes through Rho/ROCK activation. BLOOD, vol. 119, p. 2274-2283, ISSN: 0006-4971, doi: 10.1182/blood-2011-06-364083 (IF 13,168)
14.    CACCURI F, GIAGULLI C, BUGATTI A, BENETTI A, ALESSANDRI G, RIBATTI D, MARSICO S, APOSTOLI P, SLEVIN MA, RUSNATI M, GUZMAN CA, FIORENTINI S, CARUSO A. (2012). HIV-1 matrix protein p17 promotes angiogenesis via chemokine receptors CXCR1 and CXCR2. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, vol. 109, p. 14580-14585, ISSN: 1091-6490, doi: 10.1073/pnas.1206605109 (IF 9,661)
15.    BARONE I, CATALANO S, GELSOMINO L, MARSICO S, GIORDANO C, PANZA S, BONOFIGLIO D, BOSSI G, COVINGTON KR, FUQUA SA, ANDÒ S (2012). Leptin Mediates Tumor-Stromal Interactions That Promote the Invasive Growth of Breast Cancer Cells. CANCER RESEARCH, vol. 72, ISSN: 0008-5472 (IF 9,122)
16.    GUIDO C., DE AMICIS F., SANTORO M., AVENA P., PERROTTA I., CASABURI I., PANZA S., MARSICO S., ANDÒ S. (2012). Progesterone receptor B through Sp1 induces the phosphatase and tensin homologue deleted from chromosome 10 (PTEN) gene promoter activity and cell death in breast cancer cell lines. Experimental Biology Meeting, San Diego, CA, APR 21-25, 2012, FASEB JOURNAL, vol. 26, ISSN: 0892-6638. (IF 5,498)
17.    BARONE, I.,  CATALANO S.,  GELSOMINO L., PANZA S., MARSICO S., GIORDANO C., BONOFIGLIO D., CASABURI I., COVINGTON K.R., FUQUA S., ANDÒ S. (2012) Estrogen receptor-positive breast cancer cells drive cafs to secrete leptin and support tumor invasiveness. Experimental Biology Meeting, San Diego, CA, APR 21-25, 2012, FASEB JOURNAL  Vol.: 26. (IF 5,498)
18.    GIAGULLI C, MARSICO S, MAGIERA A, FIORENTINI S, BRUNO R, CARUSO A, CACCURI F. (2012) HIV-1 p17 activates PTEN and inhibits Akt signalling pathway in B cells: evidence for a p17 variant with opposite effects. 13th Annual International Meeting of the Institute of Human Virology, Baltimore, MD, OCT 30-NOV 03, 2011, JAIDS-JOURNAL OF ACQUIRED IMMUNE DEFICIENCY SYNDROMES Vol: 59, p. 79, ISSN: 1525-4135, doi: 10.1097/01.qai.0000413801.64404.23 (IF 3,935)
19.    GUIDO C, PERROTTA I, PANZA S, MIDDEA E, AVENA P, SANTORO M, MARSICO S, IMBROGNO P, ANDÒ S, AQUILA S. (2011). Human sperm physiology: estrogen receptor alpha (ERα) and estrogen receptor beta (ERβ) influence sperm metabolism and may be involved in the pathophysiology of varicocele-associated male infertility. JOURNAL OF CELLULAR PHYSIOLOGY, vol. 226, p. 3403-3412, ISSN: 1097-4652, doi: 10.1002/jcp.22703 (IF 4,08)
20.    GIAGULLI C*, MARSICO S*, MAGIERA A. K., BRUNO R., CACCURI F., BARONE I., FIORENTINI S., ANDO' S., CARUSO A. (2011). Opposite effects of HIV-1 p17 variants on PTEN activation and cell growth in B cells. PLOS ONE, vol.6, pp.123-126, ISSN: 1932-6203, doi: 10.1371/journal.pone.0017831 (IF 3,54)
21.    BRUNO ROSALINDA, MARSICO S, MININI CHIARA, APOSTOLI PAOLA, FIORENTINI SIMONA, CARUSO ARNALDO (2009). Human metapneumovirus infection in a cohort of young asymptomatic subjects. NEW MICROBIOLOGICA, vol. 32, p. 297-301, ISSN: 1121-7138 (IF 1,568)
22.    FIORENTINI S, MARSICO S, BECKER P.D, IARIA M.L, BRUNO R, GUZMAN C.A, CARUSO A (2008). Synthetic peptide AT20 coupled to KLH elicits antibodies against a conserved conformational epitope from a major functional area of the HIV-1 matrix protein p17. VACCINE, vol. 26, p. 4758-4765, ISSN: 0264-410X, doi: 10.1016/j.vaccine.2008.06.082 (IF 3,235)
23.    CATALANO S, RIZZA P, GU G, BARONE I, GIORDANO C, MARSICO S, CASABURI I, MIDDEA E, LANZINO M, PELLEGRINO M, ANDO’ S (2007). Fas ligand expression in TM4 Sertoli cells is enhanced by estradiol "in situ" production. JOURNAL OF CELLULAR PHYSIOLOGY, vol. 221, p. 448-456, ISSN: 0021-9541, doi: 10.1002/jcp.20952 (IF 4,08)
24.    AQUILA S, MIDDEA E, CATALANO S, MARSICO S, LANZINO M, CASABURI I, BARONE I, BRUNO R, ZUPO S, ANDO’ S (2007). Human sperm express a functional androgen receptor: effects on PI3K/AKT pathway. HUMAN REPRODUCTION, vol. 22, p. 2594-2605, ISSN: 0268-1161, doi: 10.1093/humrep/dem243 (IF 5,02)
25.    PANNO ML, MAURO L, MARSICO S, BELLIZZI D, RIZZA P, MORELLI C, SALERNO M, GIORDANO F, ANDO’ S (2006). Evidence that the mouse insulin receptor substrate-1 belongs to the gene family on which the promoter is activated by estrogen receptor alpha through its interaction with Sp1. JOURNAL OF MOLECULAR ENDOCRINOLOGY, vol. 36, p. 91-105, ISSN: 0952-5041, doi: 10.1677/jme.1.01846 (IF 3,577)
26.    LANZINO M, DE AMICIS F, MCPHAUL MJ, MARSICO S, PANNO ML, ANDO’ S. (2005). Endogenous coactivator ARA70 interacts with estrogen receptor alpha (ERalpha) and modulates the functional ERalpha/androgen receptor interplay in MCF-7 cells. THE JOURNAL OF BIOLOGICAL CHEMISTRY, vol. 280, p. 20421-20430, ISSN: 0021-9258, doi: 10.1074/jbc.M413576200 (IF 4,125)
27.    CATALANO S., MAURO L., MARSICO S, GIORDANO C., RIZZA P., RAGO V., MONTANARO D., MAGGIOLINI M., PANNO M.L., ANDO’ S. (2004). Leptin induces, via ERK1/ERK2 signal, functional activation of estrogen receptor alpha in MCF-7 cells. THE JOURNAL OF BIOLOGICAL CHEMISTRY, vol. 279, p. 19908-19915, ISSN: 0021-9258, doi: 10.1074/jbc.M313191200 (IF 4,125)
28.    BONOFIGLIO D., GAROFALO C., CATALANO S., MARSICO S, AQUILA S., ANDO’ S. (2004). Low calcium intake is associated with decreased adrenal androngens and reduced bone age in premenarcheal girls in the last pubertal stages. JOURNAL OF BONE AND MINERAL METABOLISM, vol. 22, p. 64-70, ISSN: 0914-8779, doi: 10.1007/s00774-003-0451-5 (IF 2,423)
29.    CATALANO S., MARSICO S, GIORDANO C., MAURO L., RIZZA P., PANNO M.L., ANDO’ S. (2003). Leptin enhances, via AP-1, expression of aromatase in the MCF-7 cell line . THE JOURNAL OF BIOLOGICAL CHEMISTRY, vol. 278, p. 28668-28676, ISSN: 0021-9258, doi: 10.1074/jbc.M301695200 (IF 4,125)
30.    MAGGIOLINI M., BONOFIGLIO D., PEZZI V., CARPINO A., MARSICO S, RAGO V., VIVACQUA A., PICARD D., ANDO’ S. (2002). Aromatase overexpression enhances the stimulatory effects of adrenal androgens on MCF7 breast cancer cells. MOLECULAR AND CELLULAR ENDOCRINOLOGY, vol. 193, p. 13-18, ISSN: 0303-7207, doi: 10.1016/S0303-7207(02)00091-6 (IF3,784)
31.    CATALANO S., AVILA D. M., MARSICO S, WILSON J. D., GLICKMAN S. E., MCPHAUL M.J. (2002). Virilization of the female spotted hyena cannot be explained by alterations in the amino acid sequence of the androgen receptor (AR). MOLECULAR AND CELLULAR ENDOCRINOLOGY, vol. 194, p. 85-94, ISSN: 0303-7207, doi: 10.1016/S0303-7207(02)00179-X (IF 3,784)
32.    MAGGIOLINI M., BONOFIGLIO D., MARSICO S, PANNO M.L., CENNI B., PICARD D., ANDO’ S. (2001). Estrogen receptor alpha mediates the proliferative but not the cytotoxic dose-dependent effects of two major phytoestrogens on human breast cancer cells. MOLECULAR PHARMACOLOGY, vol. 60, p. 595-602, ISSN: 0026-895X (IF 3,922)
33.    MAGGIOLINI M., CARPINO A., BONOFIGLIO D., PEZZI V., RAGO V., MARSICO S, PICARD D., ANDO’ S. (2001). The direct proliferative stimulus of dehydroepiandrosterone on MCF7 breast cancer cells is potentiated by overexpression of aromatase. MOLECULAR AND CELLULAR ENDOCRINOLOGY, vol. 184, p. 163-171, ISSN: 0303-7207, doi: 10.1016/S0303-7207(01)00563-9 (IF 3,784)
34.    BONOFIGLIO D., MAGGIOLINI M., CATALANO S., MARSICO S, AQUILA S., ANDO’ S. (2001). Bone mineral density is inversely related to parathyroid hormone in adolescent girls. HORMONE AND METABOLIC RESEARCH, vol. 33, p. 170-174, ISSN: 0018-5043, doi: 10.1055/s-2001-14931 (IF 2,268)
35.    BONOFIGLIO D., MAGGIOLINI M., CATALANO S., MARSICO S, AQUILA S., GIORNO A., ANDO’ S. (2000). Parathyroid hormone is elevated but bone markers and density are normal in young female subjects who consume inadequate dietary calcium. BRITISH JOURNAL OF NUTRITION, vol. 84, p. 111-116, ISSN: 0007-1145 (IF 3,706)
36.    BONOFIGLIO D, MAGGIOLINI M, MARSICO S, GIORNO A, CATALANO S, AQUILA S, ANDÒ S (1999). Critical years and stages of puberty for radial bone mass apposition during adolescence . HORMONE AND METABOLIC RESEARCH, vol. 31, p. 478-482, ISSN: 0018-5043, doi: 10.1055/s-2007-978779 (IF 2,268)
37.    MAGGIOLINI M., BONOFIGLIO D., GIORNO A., CATALANO S., MARSICO S, AQUILA S., ANDO’ S. (1999). The effect of dietary calcium intake on bone mineral density in healthy adolescent girls and young women in Southern Italy. INTERNATIONAL JOURNAL OF EPIDEMIOLOGY, vol. 28, p. 479-484, ISSN: 0300-5771, doi: 10.1093/ije/28.3.479 (IF 7,738)
38.    SISCI D, PANNO ML, SALERNO M, MAGGIOLINI M, PEZZI V, MORRONE EG, MAURO L, AQUILA S, MARSICO S, LANZINO M, ANDÒ S (1997). A time course study on the ''in vitro'' effects of T3 and testosterone on androgen and estrogen receptors in peripuberal primary rat Sertoli cells. EXPERIMENTAL AND CLINICAL ENDOCRINOLOGY & DIABETES, vol. 105, p. 218-224, ISSN: 0947-7349 (IF 1,685)
39.    M. MAGGIOLINI, G. DE LUCA, M. BRIA, V. PEZZI, A. GIORNO, D. SISCI, S. AQUILA, MARSICO S, E. CORCIONI, M. DELLA SALA, O. TAMBURRINI, C. BRANCATI, S. ANDO’. (1995). Beta-pancreatic function in polytransfused thalassemic patients. ENDOCRINOLOGY AND METABOLISM, vol. 3, p. 91-97, ISSN: 1074-939X
40.    G. DE LUCA, M. MAGGIOLINI, M. BRIA, M. CARACCIOLO, A. GIORNO, M. SALERNO, MARSICO S, M. LANZINO, C. BRANCATI, S. ANDO’. (1995). GH secretion in thalassemic patients with short stature. HORMONE RESEARCH, vol. 44, p. 158-162, ISSN: 0301-0163, doi: 10.1159/000184617

Research Interest: General Medicine Comprehensive Care Of People Living With HIV / AIDS In Resource-Limited Settings. Responsible For Information On Activities Against HIV / AIDS Conducted Ambulatory Treatment Center At The Departmental Level. Responsible For The Pole Of The Prevention Of HIV Transmission From Mother To Child

Research Interest: Hiv/Aids, Public Health, Epidemiology, Diabetes, Medical Education, General Medicine

Research Interest: Drug side effects, particularly metabolic and cardiovascular risk.