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Effectiveness of 4th doses of bivalent mRNA vaccine in reinfections from October 2022 to October 2023 in a general medicine office in Toledo (Spain) |

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    ">

      Abstract

      Open Access Research Article Article ID: ACMPH-10-307

      Effectiveness of 4th doses of bivalent mRNA vaccine in reinfections from October 2022 to October 2023 in a general medicine office in Toledo (Spain)

      Jose Luis Turabian*

      Background: The effectiveness of the COVID-19 vaccine in preventing reinfections is uncertain and there is little community-level research published at this time.

      Objective: To compare the cases of COVID-19 reinfections in vaccinated versus not vaccinated 4th dose people with bivalent mRNA vaccines and assess the effectiveness of this vaccine booster.

      Methodology: An observational, longitudinal, and prospective case series study of adult patients with COVID-19 reinfections in general medicine from October 1, 2022, to October 1, 2023. The 4th dose vaccine COVID-19 effectiveness was calculated as 1 - [COVID-19 cases incidence of reinfection with 4th dose vaccine / COVID-19 cases incidence of reinfection without 4th vaccine dose] × 100.

      Results: 12 COVID-19 reinfections were included. Of them, 5 were in people with a fourth vaccine dose of bivalent mRNA and 7 were in people without a fourth vaccine dose of bivalent mRNA. The population vaccinated with the 4th dose was estimated at 1,133 people. The population without a 4th dose was estimated at 867 people. The 4th dose of bivalent mRNA vaccine effectiveness to prevent reinfections calculated on the total number of cases of reinfections in vaccinated and unvaccinated was 30%. The 4th dose of bivalent mRNA vaccine effectiveness to prevent reinfections calculated on population denominators of the total number of people vaccinated or not, was 46%.

      Conclusion: In the context of general medicine in Toledo (Spain), the 4th dose of bivalent mRNA vaccine effectiveness to prevent reinfections was modest. However, these results should be interpreted with caution because of the few cases included and possible underreporting.

      Keywords:

      Published on: Mar 14, 2024 Pages: 1-6

      Full Text PDF Full Text HTML DOI: 10.17352/2455-5479.000207
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      Peertechz Publications Google Reviews

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      • 4.4
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      • A

      • Anna Maria

      Each step from submission to publication was handled efficiently. The review comments were accurate which increased the value of our revised manuscript. I will certainly publish more works with Peertechz.More

      • C

      • cantrella caralynn

      It was found that each step in the submission and publishing process was handled efficiently. The reviewers were clearly experts in the field and our revised manuscript was dealt with value.More

      • S

      • Samantha Wyatt

      The entire review and production process for the article has been handled with remarkable professionalism and efficiency. As the editor, I can appreciate the enormous organizational effort and discipline shown.More

      • MUSHTAQ CHALKOO

      Tomorrow is a search of today and if we research,we add an another day,that is how the time pulls on and on.Science keeps on changing its facies and thus paradigm and makes our living interesting and awesome.The knowledge of science needs to be dissipated to the progeny for better living ahead and the way we do that is through scientific journals published by different publication houses.Being associated with peertechz publications has been a wonderful experience.i have enjoyed the true spirit of scientific spice serving the organisation as an editor.It is author friendly,and makes the publication process for you very easy taking care not to jeopardise the standards of true science.I would suggest the research scholars and young scientists to associate with this publication house ,submit your reseach to brighten your career ahead in science.let us keep up the spirit of spreading the true science to the world ahead.More

      • Dr Shivaji Jadhav

      Wonderful ..process and indeed very good way in terms of communication and i recommend for publishing with this publishers...Great support.More

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